R-001: Nicotine replacement therapy for smoking cessation
| Field | Value |
|---|---|
| Research ID | R-001 |
| Authors | Stead LF, Perera R, Bullen C, et al. |
| Year | 2012 |
| Journal / publisher | Cochrane Database of Systematic Reviews |
| DOI | 10.1002/14651858.CD000146.pub4 |
| PMID | Not reported |
| ISBN | Not reported |
| Research type | Systematic Review |
| Evidence strength | Strong |
| Population | Not reported |
| Intervention | Not reported |
| Comparator | Not reported |
| Last verified | 2026-10-04 |
Main question
Does nicotine replacement therapy (NRT) help people quit smoking?
Main findings
NRT in any form (gum, patch, lozenge, inhaler, spray) increases the rate of quitting by roughly 50% to 70% compared with placebo or no medication, regardless of the setting.
Limitations
Absolute quit rates remain modest; most participants do not succeed even with NRT.
Why this record matters
Not reported
Related topics
Nicotine Replacement Therapy; Quit Methods; Quit Smoking Medications
Source
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000146.pub4/full