R-008: Pharmacological interventions for smoking cessation: an overview and network meta-analyses

Field	Value
Research ID	R-008
Authors	Cahill K, Stevens S, Perera R, Lancaster T
Year	2013
Journal / publisher	Cochrane Database of Systematic Reviews
DOI	10.1002/14651858.CD009329.pub2
PMID	Not reported
ISBN	Not reported
Research type	Meta-analysis
Evidence strength	Strong
Population	Not reported
Intervention	Not reported
Comparator	Not reported
Last verified	2026-10-04

Main question

How do the main cessation medications compare with each other?

Combination NRT and varenicline rank among the most effective options, followed by single-form NRT and bupropion, all clearly better than placebo.

Network meta-analysis assumptions; trial populations may differ from typical smokers.

Not reported

Quit Smoking Medications; Combination Approaches; Varenicline